Invention Grant
US08414890B2 Human antibodies to human RANKL, encoding nucleic acids and methods of treatment
有权
针对人RANKL的人抗体，编码核酸和治疗方法
- Patent Title: Human antibodies to human RANKL, encoding nucleic acids and methods of treatment
- Patent Title (中): 针对人RANKL的人抗体，编码核酸和治疗方法
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Application No.: US13059851Application Date: 2009-08-19
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Publication No.: US08414890B2Publication Date: 2013-04-09
- Inventor: Joel H. Martin , Aris N. Economides , Regina Raz
- Applicant: Joel H. Martin , Aris N. Economides , Regina Raz
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Merchant & Gould, P.C.
- International Application: PCT/US2009/054262 WO 20090819
- International Announcement: WO2010/022120 WO 20100225
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12N15/13 ; C07K16/30 ; C12N5/10
Abstract:
Isolated human antibodies or antigen-binding fragments thereof, which specifically bind to human RANKL and block hRANKL binding to a RANK receptor, are provided. The antibodies are useful in preventing or treating disorders and/or diseases, which are associated with RANKL/RANK interactions, including bone disorders or cancer.
Public/Granted literature
- US20120114665A1 HUMAN ANTIBODIES TO HUMAN RANKL Public/Granted day:2012-05-10
Information query
