Invention Grant
- Patent Title: Ophthalmic oil-in-water emulsions containing prostaglandins
- Patent Title (中): 含有前列腺素的眼科油包水乳剂
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Application No.: US12597528Application Date: 2008-04-24
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Publication No.: US08414904B2Publication Date: 2013-04-09
- Inventor: Fabio Carli , Mihran Baronian , Rene Schmid , Elisabetta Chiellini
- Applicant: Fabio Carli , Mihran Baronian , Rene Schmid , Elisabetta Chiellini
- Applicant Address: CH Toffen
- Assignee: AZAD Pharma AG
- Current Assignee: AZAD Pharma AG
- Current Assignee Address: CH Toffen
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: EP07008357 20070424
- International Application: PCT/EP2008/003317 WO 20080424
- International Announcement: WO2008/128779 WO 20081030
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K9/107 ; C07C405/00
Abstract:
The present invention refers to an oil-in-water emulsion for ophthalmic application comprising at least one prostaglandin as active agent and a surfactant component comprising a combination of at least two non-ionic surfactants. The emulsion is suitable for medical applications, particularly for the treatment of glaucoma, and has an increased chemical stability of the prostaglandin active agent so to allow long-term storage also at room temperature.
Public/Granted literature
- US20100112016A1 OPHTHALMIC OIL-IN-WATER EMULSIONS CONTAINING PROSTAGLANDINS Public/Granted day:2010-05-06
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