Invention Grant
- Patent Title: Preparation for treating heart disease used in cell therapy
- Patent Title (中): 用于治疗细胞治疗中使用的心脏病的制剂
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Application No.: US12681940Application Date: 2008-10-09
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Publication No.: US08414924B2Publication Date: 2013-04-09
- Inventor: Hidemasa Oh , Naofumi Takehara , Hiroaki Matsubara , Yasuhiko Tabata
- Applicant: Hidemasa Oh , Naofumi Takehara , Hiroaki Matsubara , Yasuhiko Tabata
- Applicant Address: JP Kyoto-shi, Kyoto
- Assignee: Kyoto University
- Current Assignee: Kyoto University
- Current Assignee Address: JP Kyoto-shi, Kyoto
- Agency: Fitch, Even, Tabin & Flannery, LLP
- Priority: JP2007-265008 20071010
- International Application: PCT/JP2008/068809 WO 20081009
- International Announcement: WO2009/048166 WO 20090416
- Main IPC: A61K35/34
- IPC: A61K35/34 ; A61K9/00 ; A61P9/00

Abstract:
An object of the present invention is to establish a cell transplantation method which can markedly improve the survival of grafted pluripotent stem cells and the efficiency of cardiomyocyte regeneration in cell therapy using pluripotent stem cells derived from heart tissue and can treat heart disease further effectively. Specifically, according to the present invention, enhancement in the survival of grafted pluripotent stem cells and significant improvement in the efficiency of cardiomyocyte regeneration are achieved by using, in combination, pluripotent stem cells derived from heart tissue and a hydrogel containing a basic fibroblast growth factor (bFGF) in cell therapy for heart disease.
Public/Granted literature
- US20100303909A1 PREPARATION FOR TREATING HEART DISEASE USED IN CELL THERAPY Public/Granted day:2010-12-02
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