Disclosed herein are compositions and methods for use of such for clotting blood. In one example, a disclosed composition includes at least Stachys betonica, Achillea millefolium, Marrubium vulgare, and Urtica dioica. Methods of use of the disclosed compositions are also provided, including methods of preventing or inhibiting a nosebleed, bleeding associated with a hemorrhoid or bleeding associated with a wound, such as a cut or abrasion.