Invention Grant
- Patent Title: Ketoreductases and uses thereof
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Application No.: US13290773Application Date: 2011-11-07
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Publication No.: US08415127B2Publication Date: 2013-04-09
- Inventor: Charlene Ching , John M. Gruber , Gjalt W. Huisman , Emily Mundorff , Lisa M. Newman
- Applicant: Charlene Ching , John M. Gruber , Gjalt W. Huisman , Emily Mundorff , Lisa M. Newman
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- Main IPC: C12N9/04
- IPC: C12N9/04 ; C12N1/20 ; C12N15/00 ; C12Q1/00 ; C12Q1/34 ; C12P21/04
Abstract:
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.
Public/Granted literature
- US20120178142A1 Ketoreductases and Uses Thereof Public/Granted day:2012-07-12
Information query
