Invention Grant
- Patent Title: Crystalline recombinant interferon with altered spatial configuration, three-dimensional structure and uses thereof
- Patent Title (中): 具有改变的空间构型，三维结构及其用途的结晶重组干扰素
-
Application No.: US12971956Application Date: 2010-12-17
-
Publication No.: US08415151B2Publication Date: 2013-04-09
- Inventor: Guangwen Wei , Dacheng Wang
- Applicant: Guangwen Wei , Dacheng Wang
- Agency: Law Offices of Albert Wai-Kit Chan, PLLC
- Priority: CN200910259339 20091218
- Main IPC: C07K14/555
- IPC: C07K14/555
Abstract:
This invention provides a crystalline recombinant interferon (rSIFN-co (SEQ ID NO: 1)) having (i) the same amino acid sequence as that of human consensus interferon, and (ii) altered three-dimensional structure as compared to IFN-α2b. The interferon of the present invention exhibits enhanced biological activities. The present invention also provides a structure model of said interferon useful for drug screening and/or drug design and the mimetic of said interferon.
Public/Granted literature
Information query
