Invention Grant
- Patent Title: Differentiation and enrichment of islet-like cells from human pluripotent stem cells
- Patent Title (中): 来自人多能干细胞的胰岛样细胞的分化和富集
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Application No.: US12303895Application Date: 2007-05-25
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Publication No.: US08415153B2Publication Date: 2013-04-09
- Inventor: Anish Sen Majumdar , JianJie Jiang , Melinda Au
- Applicant: Anish Sen Majumdar , JianJie Jiang , Melinda Au
- Applicant Address: US CA Menlo Park
- Assignee: Geron Corporation
- Current Assignee: Geron Corporation
- Current Assignee Address: US CA Menlo Park
- Agent Leslie A. Mooi
- International Application: PCT/US2007/012489 WO 20070525
- International Announcement: WO2007/149182 WO 20071227
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/071 ; C12N5/02

Abstract:
Methods for differentiating human pluripotent stem cells into islet-like cells are provided. In certain embodiments, the methods utilize sequential culturing of the human pluripotent stem cells with certain factors to produce islet-like cells. In certain embodiments, the population of cells produced by the methods is further enriched for islet-like cells.
Public/Granted literature
- US20100240130A1 Differentiation and Enrichment of Islet-like Cells from Human Pluripotent Stem Cells Public/Granted day:2010-09-23
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