Invention Grant
- Patent Title: Cardiomyocyte production
- Patent Title (中): 心肌细胞产生
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Application No.: US12907714Application Date: 2010-10-19
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Publication No.: US08415155B2Publication Date: 2013-04-09
- Inventor: Casey Stankewicz , Matt Riley , Nathaniel Beardsley , Wen Bo Wang , Peter Fuhrken , Steven Kattman
- Applicant: Casey Stankewicz , Matt Riley , Nathaniel Beardsley , Wen Bo Wang , Peter Fuhrken , Steven Kattman
- Applicant Address: US WI Madison
- Assignee: Cellular Dynamics International, Inc.
- Current Assignee: Cellular Dynamics International, Inc.
- Current Assignee Address: US WI Madison
- Agency: Parker Highlander PLLC
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; C12N5/08 ; C07H21/02 ; C07H21/04
Abstract:
Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.
Public/Granted literature
- US20110097799A1 CARDIOMYOCYTE PRODUCTION Public/Granted day:2011-04-28
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