Invention Grant
US08415300B2 Sustained release of microcrystalline peptide suspensions 有权
微晶肽悬浮液的持续释放

Sustained release of microcrystalline peptide suspensions
Abstract:
A fluid, milky microcrystalline aqueous suspension of a peptide or peptidomimetic and a counter-ion of a strong proton donor in water, wherein the peptide or peptidomimetic and counter-ion are present in amounts and at a molar ratio sufficient to form the suspension upon mixing and without formation of a gel. Also, lyophilized compositions that include a dried suspension, methods of making the lyophilized composition, methods of preparing the suspension, and sustained release formulations prepared by the methods.
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