Invention Grant
- Patent Title: Sustained release of microcrystalline peptide suspensions
- Patent Title (中): 微晶肽悬浮液的持续释放
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Application No.: US13224105Application Date: 2011-09-01
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Publication No.: US08415300B2Publication Date: 2013-04-09
- Inventor: Romano Deghenghi , Francois Boutignon
- Applicant: Romano Deghenghi , Francois Boutignon
- Applicant Address: GB London
- Assignee: Medical Research Council Technology
- Current Assignee: Medical Research Council Technology
- Current Assignee Address: GB London
- Agency: Winston & Strawn LLP
- Main IPC: A61K38/09
- IPC: A61K38/09 ; A61K38/00 ; A61K38/08 ; A61P43/00 ; C07K2/00 ; C07K7/06

Abstract:
A fluid, milky microcrystalline aqueous suspension of a peptide or peptidomimetic and a counter-ion of a strong proton donor in water, wherein the peptide or peptidomimetic and counter-ion are present in amounts and at a molar ratio sufficient to form the suspension upon mixing and without formation of a gel. Also, lyophilized compositions that include a dried suspension, methods of making the lyophilized composition, methods of preparing the suspension, and sustained release formulations prepared by the methods.
Public/Granted literature
- US20110312889A1 SUSTAINED RELEASE OF MICROCRYSTALLINE PEPTIDE SUSPENSIONS Public/Granted day:2011-12-22
Information query
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