Invention Grant
US08415308B2 1′-substituted-carba-nucleoside prodrugs for antiviral treatment
有权
1'-取代 - 碳 - 核苷前体进行抗病毒治疗
- Patent Title: 1′-substituted-carba-nucleoside prodrugs for antiviral treatment
- Patent Title (中): 1'-取代 - 碳 - 核苷前体进行抗病毒治疗
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Application No.: US13117060Application Date: 2011-05-26
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Publication No.: US08415308B2Publication Date: 2013-04-09
- Inventor: Aesop Cho , Choung U. Kim , Adrian S. Ray , Lijun Zhang
- Applicant: Aesop Cho , Choung U. Kim , Adrian S. Ray , Lijun Zhang
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H5/04 ; C07H7/06
Abstract:
Provided are prodrugs of pyrrolo[1,2-f][1,2,4]triazin-7-yl nucleoside phosphates wherein the 1′ position of the nucleoside sugar is substituted with CN. The compounds, compositions, and methods provided are useful for the treatment Hepatitis C infections.
Public/Granted literature
- US20120020921A1 1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT Public/Granted day:2012-01-26
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