Invention Grant
US08415324B2 Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions
失效
肝素样化合物，其制备和用途，以预防与血管损伤和干预相关的动脉血栓形成
- Patent Title: Heparin-like compounds, their preparation and use to prevent arterial thrombosis associated with vascular injury and interventions
- Patent Title (中): 肝素样化合物，其制备和用途，以预防与血管损伤和干预相关的动脉血栓形成
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Application No.: US12371195Application Date: 2009-02-13
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Publication No.: US08415324B2Publication Date: 2013-04-09
- Inventor: Riitta Lassila , Petri Kovanen , Ken Lindstedt
- Applicant: Riitta Lassila , Petri Kovanen , Ken Lindstedt
- Applicant Address: FI Helsinski
- Assignee: Jenny Ja Antti Wihurin Rahasto
- Current Assignee: Jenny Ja Antti Wihurin Rahasto
- Current Assignee Address: FI Helsinski
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: FI974321 19971125
- Main IPC: A61K31/27
- IPC: A61K31/27 ; C08B37/10 ; A01N25/28 ; C07K14/765
Abstract:
Heparin-like compounds inhibit collagen-induced platelet aggregation in flowing whole blood. The compounds share properties displayed by native mast-cell derived heparin proteoglycans (HEP-PG) and/or heparin glycosaminoglycan (HEP-GAG) molecules. The compounds are useful in prevention and treatment of severe vascular disorders including arterial thrombosis.
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