Invention Grant
US08415341B2 Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors
有权
杂芳基和芳香哌嗪基氮杂环丁烷酰胺作为单酰基甘油脂肪酶抑制剂
- Patent Title: Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors
- Patent Title (中): 杂芳基和芳香哌嗪基氮杂环丁烷酰胺作为单酰基甘油脂肪酶抑制剂
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Application No.: US12765617Application Date: 2010-04-22
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Publication No.: US08415341B2Publication Date: 2013-04-09
- Inventor: Kristen Chevalier , Jose Clemente , Scott Dax , Chris Flores , Li Liu , Mark Macielag , Mark McDonnell , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang , Bin Zhu
- Applicant: Kristen Chevalier , Jose Clemente , Scott Dax , Chris Flores , Li Liu , Mark Macielag , Mark McDonnell , Marina Nelen , Erica Nulton , Stephen Prouty , Matthew Todd , Sui-Po Zhang , Bin Zhu
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica, NV
- Current Assignee: Janssen Pharmaceutica, NV
- Current Assignee Address: BE
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/551 ; C07D401/06 ; C07D401/14 ; C07D403/12 ; C07D409/14 ; C07D417/12
Abstract:
Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the inhibition of MGL, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, r, R2 and Z are defined herein.
Public/Granted literature
- US20100324015A1 HETEROAROMATIC AND AROMATIC PIPERAZINYL AZETIDINYL AMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS Public/Granted day:2010-12-23
Information query
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