Invention Grant
- Patent Title: Inhibitors of Janus kinases
- Patent Title (中): Janus激酶抑制剂
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Application No.: US13056180Application Date: 2009-07-21
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Publication No.: US08415346B2Publication Date: 2013-04-09
- Inventor: Michael Altman , Kevin Wilson
- Applicant: Michael Altman , Kevin Wilson
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Laura M. Ginkel; David A. Muthard
- International Application: PCT/US2009/051192 WO 20090721
- International Announcement: WO2010/014453 WO 20100204
- Main IPC: A61K31/541
- IPC: A61K31/541 ; A61K31/5377 ; A61K31/496 ; C07D231/38 ; C07D413/12 ; C07D403/12 ; C07D417/12
Abstract:
The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2). The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 and TYK2 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.
Public/Granted literature
- US20110130393A1 INHIBITORS OF JANUS KINASES Public/Granted day:2011-06-02
Information query
