Invention Grant
US08415352B2 Quinoxalinone derivatives as insulin secretion stimulators, methods for obtaining them and use thereof for the treatment of diabetes
有权
喹喔啉酮衍生物作为胰岛素分泌刺激剂，获得它们的方法及其用于治疗糖尿病的用途
- Patent Title: Quinoxalinone derivatives as insulin secretion stimulators, methods for obtaining them and use thereof for the treatment of diabetes
- Patent Title (中): 喹喔啉酮衍生物作为胰岛素分泌刺激剂，获得它们的方法及其用于治疗糖尿病的用途
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Application No.: US12920736Application Date: 2009-01-15
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Publication No.: US08415352B2Publication Date: 2013-04-09
- Inventor: Gérard Botton , Eric Valeur , Micheline Kergoat , Christine Charon , Samer Elbawab
- Applicant: Gérard Botton , Eric Valeur , Micheline Kergoat , Christine Charon , Samer Elbawab
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
- Current Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: EP08004053 20080305
- International Application: PCT/EP2009/000209 WO 20090115
- International Announcement: WO2009/109258 WO 20090911
- Main IPC: A61K31/495
- IPC: A61K31/495
Abstract:
The present invention relates to quinoxalinone derivatives of formula (I): wherein R1, R2, R3, R4, R5 and R6 are as defined herein, as insulin secretion stimulators. Specific such quinoxaline compounds are also an aspect of the invention. The invention also relates to the preparation and use of these quinoxalinone derivatives for the prophylaxis and/or treatment of diabetes and pathologies associated.
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