Invention Grant
- Patent Title: Use of TAM receptor inhibitors as antimicrobials
- Patent Title (中): 使用TAM受体抑制剂作为抗微生物剂
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Application No.: US12741812Application Date: 2008-11-07
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Publication No.: US08415361B2Publication Date: 2013-04-09
- Inventor: Greg E. Lemke , John A. T. Young , Carla V. Rothlin , Suchita Bhattacharyya
- Applicant: Greg E. Lemke , John A. T. Young , Carla V. Rothlin , Suchita Bhattacharyya
- Applicant Address: US CA La Jolla
- Assignee: The Salk Institute for Biological Studies
- Current Assignee: The Salk Institute for Biological Studies
- Current Assignee Address: US CA La Jolla
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2008/082902 WO 20081107
- International Announcement: WO2009/062112 WO 20090514
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/41
Abstract:
This disclosure concerns antimicrobial compositions and methods for immunoenhancement, for example methods of increasing production of a type I interferon (IFN) in response to pathogen infection, by administration of a TAM receptor inhibitor. In certain embodiments, the disclosure concerns methods of using a TAM receptor inhibitor to treat a viral or bacterial infection in a subject.
Public/Granted literature
- US20100247554A1 USE OF TAM RECEPTOR INHIBITORS AS ANTIMICROBIALS Public/Granted day:2010-09-30
Information query
