Invention Grant
US08415362B2 Pyrazolyl substituted pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
有权
吡唑基取代的吡咯并[2,3-b]嘧啶作为Janus激酶抑制剂
![Pyrazolyl substituted pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors](/docs/US/2013-04-09/US08415362B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrazolyl substituted pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
- Patent Title (中): 吡唑基取代的吡咯并[2,3-b]嘧啶作为Janus激酶抑制剂
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Application No.: US12138082Application Date: 2008-06-12
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Publication No.: US08415362B2Publication Date: 2013-04-09
- Inventor: James D. Rodgers , Stacey Shepard , Thomas P. Maduskuie , Haisheng Wang , Nikoo Falahatpisheh , Maria Rafalski , Argyrios G. Arvanitis , Louis Storace , Ravi Kumar Jalluri
- Applicant: James D. Rodgers , Stacey Shepard , Thomas P. Maduskuie , Haisheng Wang , Nikoo Falahatpisheh , Maria Rafalski , Argyrios G. Arvanitis , Louis Storace , Ravi Kumar Jalluri
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61K31/437 ; C07D471/04 ; A61P35/00 ; A61P29/00
![Pyrazolyl substituted pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors](/abs-image/US/2013/04/09/US08415362B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines of Formula I: that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.
Public/Granted literature
- US20090181959A1 HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS Public/Granted day:2009-07-16
Information query
