Invention Grant
- Patent Title: Acid secretion inhibitor
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Application No.: US12359762Application Date: 2009-01-26
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Publication No.: US08415368B2Publication Date: 2013-04-09
- Inventor: Masahiro Kajino , Atsushi Hasuoka , Haruyuki Nishida
- Applicant: Masahiro Kajino , Atsushi Hasuoka , Haruyuki Nishida
- Applicant Address: JP Osaka-Shi
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka-Shi
- Agency: Edwards Wildman Palmer LLP
- Agent David G. Conlin; Elbert Chiang
- Priority: JP2005-250356 20050830; JP2006-100626 20060331
- Main IPC: A61K31/435
- IPC: A61K31/435 ; C07D401/06 ; C07D257/08 ; C07D257/12 ; C07D253/04 ; C07D253/06 ; C07D253/10

Abstract:
The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R2 is an optionally substituted C6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R5 is an alkyl group or a salt thereof.
Public/Granted literature
- US20090143444A1 ACID SECRETION INHIBITOR Public/Granted day:2009-06-04
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