Invention Grant
- Patent Title: Sulfonamide compound
- Patent Title (中): 磺酰胺化合物
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Application No.: US12526000Application Date: 2007-02-27
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Publication No.: US08415372B2Publication Date: 2013-04-09
- Inventor: Rintaro Yamada , Minoru Seto
- Applicant: Rintaro Yamada , Minoru Seto
- Applicant Address: JP Tokyo
- Assignee: Asahi Kasei Pharma Corporation
- Current Assignee: Asahi Kasei Pharma Corporation
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/JP2007/053567 WO 20070227
- International Announcement: WO2008/105058 WO 20080904
- Main IPC: C07D401/02
- IPC: C07D401/02 ; A61K31/47

Abstract:
A compound represented by the formula (1) [A represents a nitrogen-containing saturated ring; m represents an integer of 0 to 2; n represents an integer of 1 to 4; G1 represents hydrogen atom, chlorine atom, hydroxyl group, an alkoxy group, or amino group; G2 represents a halogen atom, hydroxyl group, cyano group, carboxy group, an alkyl group, an alkenyl group, and the like; G3 represents hydrogen atom, a halogen atom, hydroxyl group, cyano group, carboxy group, an alkyl group, an alkenyl group, and the like; G4 represents hydroxyl group, or —N(R1)(R2) (R1 and R2 represent hydrogen atom, an alkyl group, an aralkyl group, an alkenyl group, an alkynyl group, or a saturated heterocyclic group); G5 is a substituent on a ring-constituting carbon atom of A, and represents hydrogen atom, fluorine atom, or an alkyl group] or a salt thereof, or a derivative thereof that is a prodrug, which potently inhibits Rho kinase.
Public/Granted literature
- US20100093789A1 SULFONAMIDE COMPOUND Public/Granted day:2010-04-15
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