Invention Grant
US08415375B2 2-hydroxyethyl-1H-quinolin-2-one derivatives and their azaisosteric analogues with antibacterial activity
有权
2-羟乙基-1H-喹啉-2-酮衍生物及其具有抗菌活性的azaisosteric类似物
- Patent Title: 2-hydroxyethyl-1H-quinolin-2-one derivatives and their azaisosteric analogues with antibacterial activity
- Patent Title (中): 2-羟乙基-1H-喹啉-2-酮衍生物及其具有抗菌活性的azaisosteric类似物
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Application No.: US13263922Application Date: 2010-04-08
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Publication No.: US08415375B2Publication Date: 2013-04-09
- Inventor: Christian Hubschwerlen , Georg Rueedi , Jean-Philippe Surivet , Cornelia Zumbrunn Acklin
- Applicant: Christian Hubschwerlen , Georg Rueedi , Jean-Philippe Surivet , Cornelia Zumbrunn Acklin
- Applicant Address: CH Allschwil
- Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee Address: CH Allschwil
- Agency: Hunton & Williams LLP
- Priority: WOPCT/IB2009/051510 20090409
- International Application: PCT/IB2010/051517 WO 20100408
- International Announcement: WO2010/116337 WO 20101014
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/47
Abstract:
The invention relates to antibacterial compounds of formula I wherein R1 represents alkoxy; each of U and V represents CH and W represents CH or N, or U represents N, V represents CH and W represents N, or each of U and V represents N and W represents CH; R2 represents hydrogen or fluorine when W represents CH or R2 represents hydrogen when W represents N; A represents O or CH2; Y represents CH or N; Q represents O or S; and n represents 0 or 1; and salts of such compounds.
Public/Granted literature
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