Invention Grant
- Patent Title: Triazole compounds that modulate HSP90 activity
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Application No.: US13229178Application Date: 2011-09-09
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Publication No.: US08415377B2Publication Date: 2013-04-09
- Inventor: Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Przewloka , Shijie Zhang , Dinesh Chimmanamada , Kevin Foley , Zhenjian Du , Hao Li , David James , Howard Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- Applicant: Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Przewloka , Shijie Zhang , Dinesh Chimmanamada , Kevin Foley , Zhenjian Du , Hao Li , David James , Howard Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D403/04 ; A61K31/4196 ; A61K31/4709

Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Public/Granted literature
- US20110319447A1 TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY Public/Granted day:2011-12-29
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