Invention Grant
- Patent Title: Pharmaceutical compositions containing paclitaxel orotate
- Patent Title (中): 含有紫杉醇乳清酸的药物组合物
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Application No.: US13066793Application Date: 2011-04-25
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Publication No.: US08415388B2Publication Date: 2013-04-09
- Inventor: Rashida A. Karmali
- Applicant: Rashida A. Karmali
- Applicant Address: US NY New York
- Assignee: Savvipharm Inc.
- Current Assignee: Savvipharm Inc.
- Current Assignee Address: US NY New York
- Agent Rashida A. Karmali
- Main IPC: A61K31/335
- IPC: A61K31/335 ; C07D305/14

Abstract:
This invention is related to orotic acid compounds of taxane cytotoxic agents and in particular to the conversion of the taxanes to their orotate esters. More particularly the pharmaceutical compositions of paclitaxel orotate and docetaxel orotate provide a strategy to minimize body weight loss during primary chemotherapy and improve patient outcomes and quality of life.
Public/Granted literature
- US20120197017A1 Pharmaceutical compositions containing paclitaxel orotate Public/Granted day:2012-08-02
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