Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

Invention Grant

US08415468B2 Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid 有权

Title translation: 将伊伐布拉德及其加成盐与药学上可接受的酸合成的方法

Patent Title: Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
Patent Title (中): 将伊伐布拉德及其加成盐与药学上可接受的酸合成的方法
Application No.: US13138333

Application Date: 2010-02-03
Publication No.: US08415468B2

Publication Date: 2013-04-09
Inventor: Jean-Louis Peglion , Aimee Dessinges , Bernard Serkiz , Jean-Michel Lerestif , Jean-Pierre Lecouve
Applicant: Jean-Louis Peglion , Aimee Dessinges , Bernard Serkiz , Jean-Michel Lerestif , Jean-Pierre Lecouve
Applicant Address: FR Suresnes Cedex
Assignee: Les Laboratoires Servier
Current Assignee: Les Laboratoires Servier
Current Assignee Address: FR Suresnes Cedex
Agency: Hueschen and Sage
Priority: FR0900457 20090204
International Application: PCT/FR2010/000080 WO 20100203
International Announcement: WO2010/089475 WO 20100812
Main IPC: C07D223/16
IPC: C07D223/16 ; C07C303/00 ; C07C22/00

Abstract:

Process for the synthesis of ivabradine of formula (I): and addition salts thereof with a pharmaceutically acceptable acid.

Abstract(Chinese):

用于合成式（I）的伊伐布拉定的方法及其与药学上可接受的酸的加成盐。

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