Invention Grant
US08415472B2 Water soluble photochromic compounds for labeling of biomolecules and method for detecting biomolecules using the same
有权
用于标记生物分子的水溶性光致变色化合物及其用于检测生物分子的方法
- Patent Title: Water soluble photochromic compounds for labeling of biomolecules and method for detecting biomolecules using the same
- Patent Title (中): 用于标记生物分子的水溶性光致变色化合物及其用于检测生物分子的方法
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Application No.: US12739601Application Date: 2008-08-21
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Publication No.: US08415472B2Publication Date: 2013-04-09
- Inventor: Bony Hyun Chung , Sang Jeon Chung , Suh Hyun Lee , Im Sik Chung , Hyun Kyu Park , Chang Soo Lee
- Applicant: Bony Hyun Chung , Sang Jeon Chung , Suh Hyun Lee , Im Sik Chung , Hyun Kyu Park , Chang Soo Lee
- Applicant Address: KR Daejeon
- Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee Address: KR Daejeon
- Agency: Moore & Van Allen, PLLC
- Agent Andrew D. Gerschutz; Tristan A. Fuierer
- Priority: KR10-2007-0107245 20071024
- International Application: PCT/KR2008/004882 WO 20080821
- International Announcement: WO2009/054608 WO 20090430
- Main IPC: C07D237/26
- IPC: C07D237/26
Abstract:
The present invention relates to water-soluble photochromic compounds for labeling biomolecules and a method of detecting biomolecules using the same. More specifically, relates to water-soluble photochromic compounds for labeling biomolecules, in which a functional group rendering photochromic molecules water-soluble is linked to a functional group capable of binding to biomolecules, and a method of detecting biomolecules using the same. Because the disclosed water-soluble photochromic compounds exhibit the color corresponding to the wavelength of visible light range, they allow signals to be easily detected not only with an UV-VIS spectrophotometer but also visually. Accordingly, the photochromic compounds can be advantageously used in sensors for diagnosing diseases.
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