The present disclosure relates to an adjustable bed system including a bed frame that is adjustable in height. In one aspect of the present disclosure, the adjustable bed system includes first and second end boards each having an independent height adjustment mechanism. A frame assembly configured and dimensioned to be secured to the first end board at a first end thereof and to the second end board at a second end thereof includes a frame and a transition box. The transition box is secured to the frame at the first end thereof and is operatively engagable with the height adjustment mechanism of the first end board. A drive shaft adjustable between first and second lengths is coupled at a first end thereof to the transition box and at a second end thereof to the second end board to facilitate uniform height adjustment of the first and second end boards.