Invention Grant
US08420071B2 Herpes simplex virus expressing foreign genes and method for treating cancers therewith
失效
表达外源基因的单纯疱疹病毒和用于治疗癌症的方法
- Patent Title: Herpes simplex virus expressing foreign genes and method for treating cancers therewith
- Patent Title (中): 表达外源基因的单纯疱疹病毒和用于治疗癌症的方法
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Application No.: US12234246Application Date: 2008-09-19
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Publication No.: US08420071B2Publication Date: 2013-04-16
- Inventor: Richard J. Whitley , James MacDowell Markert , George Yancey Gillespie , Jacqueline Nuss Parker
- Applicant: Richard J. Whitley , James MacDowell Markert , George Yancey Gillespie , Jacqueline Nuss Parker
- Applicant Address: US AL Birmingham
- Assignee: The UAB Research Foundation
- Current Assignee: The UAB Research Foundation
- Current Assignee Address: US AL Birmingham
- Agency: Blue Filament Law PLLC
- Agent Avery N. Goldstein
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K48/00
Abstract:
An anti-cancer pharmaceutical composition includes a herpes simplex virus (HSV) vector into which a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD has been inserted. A method of treatment of a patient suffering from cancer includes administering to the patient the anti-tumor pharmaceutical composition including a HSV vector having a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD inserted therein.
Public/Granted literature
- US20090186003A1 HERPES SIMPLEX VIRUS EXPRESSING FOREIGN GENES AND METHOD FOR TREATING CANCERS THEREWITH Public/Granted day:2009-07-23
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