Invention Grant
- Patent Title: Recombinantly modified plasmin
- Patent Title (中): 重组修饰的纤溶酶
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Application No.: US13223373Application Date: 2011-09-01
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Publication No.: US08420079B2Publication Date: 2013-04-16
- Inventor: Jennifer Hunt , Valery Novokhatny
- Applicant: Jennifer Hunt , Valery Novokhatny
- Applicant Address: US NC Research Triangle Park
- Assignee: Grifols Therapeutics, Inc.
- Current Assignee: Grifols Therapeutics, Inc.
- Current Assignee Address: US NC Research Triangle Park
- Agency: Womble Carlyle Sandridge & Rice, LLP
- Main IPC: A61K38/48
- IPC: A61K38/48 ; C12N9/50 ; A01N43/04
Abstract:
Polynucleotides and polypeptides relating to a recombinantly-modified plasmin(ogen) molecule are provided. The plasmin(ogen) molecule has a single kringle domain N-terminal to the activation site present in the native human plasminogen molecule, and exhibits lysine-binding and significant enzymatic characteristics associated with the native enzyme.
Public/Granted literature
- US20110318812A1 Recombinantly Modified Plasmin Public/Granted day:2011-12-29
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