Invention Grant
US08420090B2 Recombinant B. pseudomallei adhesin protein and methods and uses thereof
失效
重组假单胞菌粘附素蛋白及其方法和用途
- Patent Title: Recombinant B. pseudomallei adhesin protein and methods and uses thereof
- Patent Title (中): 重组假单胞菌粘附素蛋白及其方法和用途
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Application No.: US13252677Application Date: 2011-10-04
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Publication No.: US08420090B2Publication Date: 2013-04-16
- Inventor: Chad Wesley Stratilo , Scott James Jager
- Applicant: Chad Wesley Stratilo , Scott James Jager
- Applicant Address: CA Ottawa
- Assignee: Her Majesty the Queen in Right of Canada as Represented by the Minister of National Defence
- Current Assignee: Her Majesty the Queen in Right of Canada as Represented by the Minister of National Defence
- Current Assignee Address: CA Ottawa
- Agency: Blake, Cassels & Graydon LLP
- Agent Santosh K. Chari
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; A61K39/40 ; C12N5/07 ; C12P21/08
Abstract:
Isolated and/or recombinant adhesin polypeptides from Burkholderia pseudomallei are provided, which are used as vaccines. Genetic constructs comprising nucleic acid sequences encoding such polypeptides are also provided. Vectors comprising such constructs have been prepared and used for transforming host cells for producing the polypeptides of the invention. Antibodies to such polypeptides are also provided. Such antibodies can be used to detect the presence of B. pseudomallei or B. mallei and in methods of treating or preventing Burkholderia infection.
Public/Granted literature
- US20120087924A1 Recombinant B. pseudomallei Adhesin Protein and Methods and Uses Thereof Public/Granted day:2012-04-12
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