Invention Grant
- Patent Title: Papillomavirus vaccines
- Patent Title (中): 乳头瘤病毒疫苗
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Application No.: US12449197Application Date: 2008-01-29
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Publication No.: US08420103B2Publication Date: 2013-04-16
- Inventor: Martine Baudin , Jean-Marc Balloul , Nathalie Silvestre
- Applicant: Martine Baudin , Jean-Marc Balloul , Nathalie Silvestre
- Applicant Address: FR Illkirch
- Assignee: Transgene S.A.
- Current Assignee: Transgene S.A.
- Current Assignee Address: FR Illkirch
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: EP07360004 20070130; EP07360018 20070515
- International Application: PCT/EP2008/051032 WO 20080129
- International Announcement: WO2008/092854 WO 20080807
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12N15/63 ; A61P31/12

Abstract:
A nucleic acid molecule encoding at least one papillomavirus E2 polypeptide, or a vector, an infectious viral particle or a therapeutic composition thereof is formulated into a drug product useful for treating a patient suffering from a persistent papillomavirus infection caused by at least one papillomavirus; particular such vectors are nucleic acid molecules containing a first nucleotide sequence encoding a papillomavirus E1 polypeptide and a second nucleotide sequence encoding a papillomavirus E2 polypeptide wherein the 3′ portion of the first nucleotide which in the natural content is 100% identical to the 5′ portion of the second nucleotide is modified so as to exhibit a percentage of identity between said portions of at most 75%.
Public/Granted literature
- US20100143408A1 PAPILLOMAVIRUS VACCINES Public/Granted day:2010-06-10
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