Invention Grant
- Patent Title: Oral preparations and process for production thereof
- Patent Title (中): 口服制剂及其制备方法
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Application No.: US11628062Application Date: 2005-05-25
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Publication No.: US08420115B2Publication Date: 2013-04-16
- Inventor: Hiroshi Ikuta , Toshio Yajima
- Applicant: Hiroshi Ikuta , Toshio Yajima
- Applicant Address: JP Tokyo
- Assignee: Taisho Pharmaceutical Co., Ltd.
- Current Assignee: Taisho Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2004-165654 20040603
- International Application: PCT/JP2005/009509 WO 20050525
- International Announcement: WO2005/117845 WO 20051215
- Main IPC: A61K9/10
- IPC: A61K9/10

Abstract:
Disclosed herein are oral preparations and their production process. The oral preparations are each composed of a complex and a coating composition applied on the complex. The complex has been obtained by dispersing or dissolving a drug having an unpleasant taste and a gastric high-molecular compound in a low melting-point substance heated to and molten at its melting point or higher and granulating the resulting mixture. The coating composition is composed of an insoluble high-molecular compound and a disintegrator at a weight ratio of from 80:20 to 99:1. In the form of microparticles or the like that contain the drug having the unpleasant taste, each oral preparation according to the present invention can maintain the masking of the unpleasant taste of the drug and the release profile of the drug even under acidic conditions.
Public/Granted literature
- US20080031965A1 Oral Preparations and Process for Production Thereof Public/Granted day:2008-02-07
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