Invention Grant
- Patent Title: Drug composition for treating tumor with polymeric micelle encapsulating anti-neoplastic
- Patent Title (中): 用聚合胶束包封抗肿瘤剂治疗肿瘤的药物组合物
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Application No.: US13265802Application Date: 2009-08-20
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Publication No.: US08420119B2Publication Date: 2013-04-16
- Inventor: Yuan-Hung Hsu , Chu-Chun Hsueh , Yuan-Chia Chang , Jui-Mei Lu , Pei Kan
- Applicant: Yuan-Hung Hsu , Chu-Chun Hsueh , Yuan-Chia Chang , Jui-Mei Lu , Pei Kan
- Applicant Address: TW Hsinchu
- Assignee: Industrial Technology Research Institute
- Current Assignee: Industrial Technology Research Institute
- Current Assignee Address: TW Hsinchu
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: CN200910132138 20090421
- International Application: PCT/CN2009/073382 WO 20090820
- International Announcement: WO2010/121455 WO 20101028
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/51 ; A61K31/44 ; A01N43/42

Abstract:
This present disclosure relates to pharmaceutical compositions for treating tumors using a polymeric micelle encapsulating an anti-tumor drug. The polymeric micelle comprises block copolymers comprising at least one hydrophilic block, at least one hydrophobic block, and at least one zwitterion. The present disclosure also relates to methods of enhancing the solubility of such drugs, methods of increasing the blood circulating time of such drugs, and methods of delivering such drugs to one or more solid tumors.
Public/Granted literature
- US20120100220A1 DRUG COMPOSITION FOR TREATING TUMOR WITH POLYMERIC MICELLE ENCAPSULATING ANTI-NEOPLASTIC Public/Granted day:2012-04-26
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