Invention Grant
- Patent Title: Crystals of human glutamic acid decarboxylase 65 (GAD65)
- Patent Title (中): 人谷氨酸脱羧酶65（GAD65）的晶体
-
Application No.: US12310958Application Date: 2007-09-13
-
Publication No.: US08420371B2Publication Date: 2013-04-16
- Inventor: James Charles Whisstock , Ashley Maurice Buckle , Gustavo Fenalti , Ruby Hong Ping Law , Merrill Joy Rowley
- Applicant: James Charles Whisstock , Ashley Maurice Buckle , Gustavo Fenalti , Ruby Hong Ping Law , Merrill Joy Rowley
- Applicant Address: AU Clayton
- Assignee: Monash University
- Current Assignee: Monash University
- Current Assignee Address: AU Clayton
- Agency: Ohlandt, Greeley, Ruggiero & Perle, LLP.
- Priority: AU2006905117 20060915
- International Application: PCT/AU2007/001362 WO 20070913
- International Announcement: WO2008/031164 WO 20080320
- Main IPC: C12N9/88
- IPC: C12N9/88
Abstract:
A crystal comprising an isoform of an N-terminally truncated glutamic acid decarboxylase (GAD) chosen from the group consisting of a monoclinic P21 space group with unit cell dimensions of a =84.05±2.3 Å, b=62.74±2.3 Å, c=101.35±2.3 Å and β =106.69° (GAD67) or an orthorhombic C2221 space group with unit cell dimensions of a=78.25±2.3 Å, b=99.05±2.3 Å and c=120.01±2.3 Å(GAD65).
Public/Granted literature
- US20100216112A1 Crystal structures of both isoforms of human glutamic acid decarboxylase Public/Granted day:2010-08-26
Information query
