Invention Grant
- Patent Title: Diabetes treatment methods and drug targets therefor
- Patent Title (中): 糖尿病治疗方法及药物靶标
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Application No.: US11625795Application Date: 2007-01-22
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Publication No.: US08420612B2Publication Date: 2013-04-16
- Inventor: Kenneth Chien , Lisa Lesniewski , Jerrold Olefsky , Mohammad Pashmforoush
- Applicant: Kenneth Chien , Lisa Lesniewski , Jerrold Olefsky , Mohammad Pashmforoush
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Sutherland Asbill & Brennan LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/11 ; A01N63/00 ; C12N15/00 ; C12N5/00 ; C12N5/071
Abstract:
Provided are methods of treating insulin resistance or type II diabetes. Disrupting CAP in the macrophage can alter the inflammatory response associated with impaired insulin action and ultimately result in improved insulin action in target tissues. One aspect of the invention involves administering a CAP antagonist to a patient afflicted with insulin resistance or type II diabetes in an amount sufficient to improve insulin action in target tissues.
Public/Granted literature
- US20070190035A1 Diabetes Treatment Methods and Drug Targets Therefor Public/Granted day:2007-08-16
Information query
