Invention Grant
US08420623B2 N, N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
有权
可用作单胺再摄取抑制剂的N,N-取代的3-氨基吡咯烷化合物
- Patent Title: N, N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
- Patent Title (中): 可用作单胺再摄取抑制剂的N,N-取代的3-氨基吡咯烷化合物
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Application No.: US13298336Application Date: 2011-11-17
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Publication No.: US08420623B2Publication Date: 2013-04-16
- Inventor: Muneaki Kurimura , Shinichi Taira , Takahiro Tomoyasu , Nobuaki Ito , Kuninori Tai , Noriaki Takemura , Takayuki Matsuzaki , Yasuhiro Menjo , Shin Miyamura , Yohji Sakurai , Akihito Watanabe , Yasuyo Sakata , Takumi Masumoto , Kohei Akazawa , Haruhiko Sugino , Naoki Amada , Satoshi Ohashi , Tomoichi Shinohara , Hirofumi Sasaki , Chisako Morita , Junko Yamashita , Satoko Nakajima
- Applicant: Muneaki Kurimura , Shinichi Taira , Takahiro Tomoyasu , Nobuaki Ito , Kuninori Tai , Noriaki Takemura , Takayuki Matsuzaki , Yasuhiro Menjo , Shin Miyamura , Yohji Sakurai , Akihito Watanabe , Yasuyo Sakata , Takumi Masumoto , Kohei Akazawa , Haruhiko Sugino , Naoki Amada , Satoshi Ohashi , Tomoichi Shinohara , Hirofumi Sasaki , Chisako Morita , Junko Yamashita , Satoko Nakajima
- Applicant Address: JP Tokyo
- Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2005-141230 20050513
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/497 ; A61K31/538 ; A61K31/695 ; A61K31/501 ; C07D207/12 ; C07D241/20 ; C07D403/12 ; C07D498/04

Abstract:
The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.
Public/Granted literature
- US20120065162A1 N-N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS Public/Granted day:2012-03-15
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