Invention Grant
- Patent Title: Pyridine derivatives useful as glucokinase activators
- Patent Title (中): 用作葡糖激酶活化剂的吡啶衍生物
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Application No.: US12682055Application Date: 2008-08-13
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Publication No.: US08420642B2Publication Date: 2013-04-16
- Inventor: Lars Thore Burgdorf , Norbert Beier , Johannes Gleitz , Christine Charon , Daniel Cravo
- Applicant: Lars Thore Burgdorf , Norbert Beier , Johannes Gleitz , Christine Charon , Daniel Cravo
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: EP07019691 20071009; EP08001168 20080123
- International Application: PCT/EP2008/006649 WO 20080813
- International Announcement: WO2009/046784 WO 20090416
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/4439 ; A61K31/444 ; A61K31/4545 ; C07D417/12 ; C07D401/12 ; C07D417/14 ; A61P3/10 ; A61P13/12
Abstract:
Novel heterocyclic compounds of the formula I in which R1, R2, R3, R4 and D have the meanings indicated in Claim 1, are activators of glucokinase and can be used for the prevention and/or treatment of Diabetes Typ 1 and 2, obesity, neuropathy and/or nephropathy.
Public/Granted literature
- US20100216794A1 PYRIDINE DERIVATIVES USEFUL AS GLUCOKINASE ACTIVATORS Public/Granted day:2010-08-26
Information query
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