Invention Grant
US08420647B2 4-phenoxy-nicotinamide or 4-phenoxy-pyrimidine-5-carboxamide compounds
失效
4-苯氧基 - 烟酰胺或4-苯氧基 - 嘧啶-5-甲酰胺化合物
- Patent Title: 4-phenoxy-nicotinamide or 4-phenoxy-pyrimidine-5-carboxamide compounds
- Patent Title (中): 4-苯氧基 - 烟酰胺或4-苯氧基 - 嘧啶-5-甲酰胺化合物
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Application No.: US13005566Application Date: 2011-01-13
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Publication No.: US08420647B2Publication Date: 2013-04-16
- Inventor: Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ulmer
- Applicant: Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ulmer
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Gene J. Yao
- Priority: EP10151319 20100121
- Main IPC: A61K31/498
- IPC: A61K31/498
Abstract:
This invention relates to novel phenyl amide or pyridyl amide derivatives of the formula wherein A1, A2, B1, B2 and R1 to R11 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
Public/Granted literature
- US20110178089A1 4-PHENOXY-NICOTINAMIDE OR 4-PHENOXY-PYRIMIDINE-5-CARBOXAMIDE COMPOUNDS Public/Granted day:2011-07-21
Information query
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