Invention Grant
- Patent Title: Aminotetrahydroindazoloacetic acids
- Patent Title (中): 氨基四氢吲唑并乙酸
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Application No.: US13342150Application Date: 2012-01-02
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Publication No.: US08420675B2Publication Date: 2013-04-16
- Inventor: Li Chen , Fariborz Firooznia , Paul Gillespie , Yun He , Tai-An Lin , Sung-Sau So , HongYing Yun , Zhenshan Zhang
- Applicant: Li Chen , Fariborz Firooznia , Paul Gillespie , Yun He , Tai-An Lin , Sung-Sau So , HongYing Yun , Zhenshan Zhang
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Dennis P. Tramaloni; Brian C. Remy
- Main IPC: A61K31/416
- IPC: A61K31/416 ; A61K31/4439 ; A61K31/4245 ; C07D413/12 ; C07D401/12 ; C07D231/54
Abstract:
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, W, X, R1—R5 and n are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
Public/Granted literature
- US20120101131A1 Aminotetrahydroindazoloacetic Acids Public/Granted day:2012-04-26
Information query
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