Invention Grant
- Patent Title: Inhibitors of janus kinases
- Patent Title (中): 痛风激酶抑制剂
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Application No.: US13002776Application Date: 2009-07-01
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Publication No.: US08420695B2Publication Date: 2013-04-16
- Inventor: Kevin Wilson , Gabriela de Almeida , Andrew Haidle , Kaleen Konrad , Michelle Machacek , Ann Zabierek
- Applicant: Kevin Wilson , Gabriela de Almeida , Andrew Haidle , Kaleen Konrad , Michelle Machacek , Ann Zabierek
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Laura M. Ginkel; David A. Muthard
- International Application: PCT/US2009/049357 WO 20090701
- International Announcement: WO2010/005841 WO 20100114
- Main IPC: A61K31/38
- IPC: A61K31/38 ; C07D333/36 ; C07D333/42
Abstract:
The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2). The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 and TYK2 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.
Public/Granted literature
- US20110112081A1 INHIBITORS OF JANUS KINASES Public/Granted day:2011-05-12
Information query
