Invention Grant
- Patent Title: Modular DNA-binding domains and methods of use
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Application No.: US13362660Application Date: 2012-01-31
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Publication No.: US08420782B2Publication Date: 2013-04-16
- Inventor: Ulla Bonas , Jens Boch , Sebastian Schornack , Thomas Lahaye
- Applicant: Ulla Bonas , Jens Boch , Sebastian Schornack , Thomas Lahaye
- Agency: Alston & Bird LLP
- Priority: DE102009004659 20090112; EP09165328 20090713
- Main IPC: C07K1/00
- IPC: C07K1/00 ; C07K14/00 ; C07K17/00 ; A61K38/16 ; C12P1/00 ; C12P21/06 ; C12P21/04 ; C12N9/14 ; C12N9/16 ; C12N9/22 ; C12N15/00 ; C12N15/88
Abstract:
The present invention refers to methods for selectively recognizing a base pair in a DNA sequence by a polypeptide, to modified polypeptides which specifically recognize one or more base pairs in a DNA sequence and, to DNA which is modified so that it can be specifically recognized by a polypeptide and to uses of the polypeptide and DNA in specific DNA targeting as well as to methods of modulating expression of target genes in a cell.
Public/Granted literature
- US20120122205A1 MODULAR DNA-BINDING DOMAINS AND METHODS OF USE Public/Granted day:2012-05-17
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