Invention Grant
- Patent Title: Bicyclic heterocyclic compound
- Patent Title (中): 双环杂环化合物
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Application No.: US12597302Application Date: 2008-04-25
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Publication No.: US08420810B2Publication Date: 2013-04-16
- Inventor: Tetsuji Saito , Tetsuo Obitsu , Yoshifumi Kagamiishi
- Applicant: Tetsuji Saito , Tetsuo Obitsu , Yoshifumi Kagamiishi
- Applicant Address: JP Osaka
- Assignee: Ono Pharmaceutical, Co., Ltd.
- Current Assignee: Ono Pharmaceutical, Co., Ltd.
- Current Assignee Address: JP Osaka
- Agency: Sughrue Mion, PLLC
- Priority: JP2007-117757 20070426; JP2007-294024 20071113; JP2008-026456 20080206
- International Application: PCT/JP2008/058014 WO 20080425
- International Announcement: WO2008/136377 WO 20081113
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/53 ; A61P3/04 ; A61P15/12 ; A61P25/18 ; A61P25/22 ; A61P25/24 ; A61P25/30 ; A61P25/32

Abstract:
A compound of a formula (I): wherein R1 represents a C3-10 branched alkyl group which may be substituted; R2 represents a hydrogen atom or a C1-4 alkyl group which may be substituted; R3 represents a C1-4 alkyl group which may be substituted or a halogen atom; R4 represents a C1-4 alkyl group which may be substituted; and ring 1 represents a cyclic group which has planarity and may have a substituent group, a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug thereof, is useful as a medicinal component having CRF antagonistic activity for the prevention and/or treatment of a neuropsychiatric disease, a peripheral organ disease and the like.
Public/Granted literature
- US20100137318A1 BICYCLIC HETEROCYCLIC COMPOUND Public/Granted day:2010-06-03
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