Invention Grant
- Patent Title: Process for optimizing the particle size of an active pharmaceutical ingredient by crystallization
- Patent Title (中): 通过结晶优化活性药物成分的粒径的方法
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Application No.: US12788562Application Date: 2010-05-27
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Publication No.: US08420819B2Publication Date: 2013-04-16
- Inventor: Soojin Kim
- Applicant: Soojin Kim
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Timothy X. Witkowski; Usha R. Patel
- Main IPC: C07D471/04
- IPC: C07D471/04

Abstract:
A process to crystallize uniform small particles of a compound of Formula (I) with narrow particle size distribution and excellent powder characteristics that facilitate the formulation process and optimal drug product performance, wherein the compound of Formula (I) is: wherein R1, R2, and R3 are as described herein.
Public/Granted literature
- US20100311978A1 PROCESS FOR OPTIMIZING THE PARTICLE SIZE OF AN ACTIVE PHARMACEUTICAL INGREDIENT BY CRYSTALLIZATION Public/Granted day:2010-12-09
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