In general, techniques are described for dynamically configuring cross-domain pseudowires (PWs). A network device positioned between a first domain and a second domain of a computer network may implement the techniques. The intermediate network device comprises at least one interface and an LDP module, a transformation module and a routing protocol module. The interface receives a label distribution protocol (LDP) message that includes data for configuring a cross-domain PW from a first provider edge (PE) device of the first domain. The LDP module parses the received LDP message to extract the cross-domain PW configuration data. The translation module transforms the extracted data to conform to routing protocol extensions for advertising the cross-domain PW configuration data. The routing protocol module forms a routing protocol message that includes the transformed data. The interface outputs the routing protocol message to the second intermediate device of the second domain to establish the cross-domain PW.