A differential signal receiver 106 implements intra-pair skew compensation for improving data transfer on a differential channel. In an embodiment, the receiver implements sampling by—multiple clocks with different phases such that the signals of the differential channel may be separately or individually time adjusted to account for skew between them so that they may be differentially compared for data resolution. In one embodiment, a positive sampler and negative sampler are controlled by distinct clock signals to permit, at different times, sampling and holding of the positive and negative signals representing a data bit on the differential channel. A differential decision circuit may then differentially resolve the data using a latter one of the distinct clock signals. Timing generation circuitry for producing the offset clocks may include a skew detector that permits dynamic adjustment of the different clock signals according to skew associated with the signals of the differential channel.