A catheter assembly and method of using the catheter assembly is provided herein. The catheter assembly has a catheter shaft having an elongated body extending about a longitudinal axis, a proximal portion and a distal portion, an outer surface, and at least one lumen extending therethrough the elongated body at least one means for sealing at least a portion of the lumen of the bronchial vessel. At least a portion of the catheter assembly is configured for insertion into at least a portion of a bronchial vessel of a target lung region. The means for sealing is moveable between a collapsed state and an expanded state. At least a portion of the vessel can be sealed by inflating the means for sealing. The catheter assembly can then be used to infuse a dialysate solution into the target lung region.