A suture lock fastening device to cinch a suture in a suture lock, cut the suture end, and deploy the suture lock in response to a single movement of a user. The fastening device includes a fastening head with a retainer that is configured to hold a suture lock in the fastening head. To release the suture lock from the fastening head, the retainer is irreversibly deformed. The fastening device may include an axially movable cutter with a cutting edge to sever the ends of the suture close to the suture lock. A threading device may be preloaded into the fastening device to facilitate threading the suture through the fastening device.