The present disclosure is directed towards systems and methods for the treatment of wastewater. A system in accordance with one particular embodiment may include an oxidation reactor configured to receive a flow of wastewater from a wastewater producing process. The oxidation reactor may be further configured to oxidize a chemical associated with the flow of wastewater with an oxidation agent. The oxidation reactor may include at least one reaction member configured to pressurize at least a portion of the oxidation reactor. The system may further include at least one resin tank configured to contain an ion exchange resin configured to target a particular metal, the at least one resin tank configured to receive an output from the oxidation reactor. Numerous other embodiments are also within the scope of the present disclosure.