Invention Grant
- Patent Title: Method for analyzing the effect of a gaseous medium on a biological test system using an extracellular metabolization system
- Patent Title (中): 使用细胞外代谢系统分析气体介质对生物测试系统的影响的方法
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Application No.: US12452154Application Date: 2008-06-16
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Publication No.: US08426157B2Publication Date: 2013-04-23
- Inventor: Jan Knebel , Detlef Ritter
- Applicant: Jan Knebel , Detlef Ritter
- Applicant Address: DE Munich
- Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
- Current Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
- Current Assignee Address: DE Munich
- Agency: Collard & Roe, P.C.
- Priority: DE102007030413 20070629
- International Application: PCT/DE2008/001007 WO 20080616
- International Announcement: WO2009/003441 WO 20090108
- Main IPC: C12Q1/02
- IPC: C12Q1/02
Abstract:
The invention relates to a method for analyzing the effect of a gaseous medium on a biological test system using an extracellular metabolization system. The method consists of the following steps: a biological test sample is cultivated on a permeable carrier, the gaseous medium is guided over the surface of the biological test system in order to form an exposition atmosphere over the biological test system, the extracellular metabolization system is added to a conservation medium and the permeable carrier is brought into contact with a conservation medium that comprises the extracellular metabolization system below the permeable carrier, in such a manner that the extracellular metabolization system only passes through the permeable carrier and that the biological test system is not submerged by the conservation medium containing the extracellular metabolization system.
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