Invention Grant
US08426169B2 Glycosylate derivatives of mithramycin, method of preparation and uses thereof
有权
木霉素的磺酸酯衍生物，其制备方法及其应用
- Patent Title: Glycosylate derivatives of mithramycin, method of preparation and uses thereof
- Patent Title (中): 木霉素的磺酸酯衍生物，其制备方法及其应用
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Application No.: US12525695Application Date: 2008-02-04
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Publication No.: US08426169B2Publication Date: 2013-04-23
- Inventor: Jürgen Rohr , Irfan Baig , José Antonio Salas Fernández , Alfredo Fernández Braña , Carmen Méndez Fernández , Mariá Pérez Solares
- Applicant: Jürgen Rohr , Irfan Baig , José Antonio Salas Fernández , Alfredo Fernández Braña , Carmen Méndez Fernández , Mariá Pérez Solares
- Applicant Address: US KY Lexington ES Oviedo
- Assignee: University of Kentucky Research Foundation,Universidad de Oviedo
- Current Assignee: University of Kentucky Research Foundation,Universidad de Oviedo
- Current Assignee Address: US KY Lexington ES Oviedo
- Agency: Moore & Van Allen, PLLC
- Agent Tristan A. Fuierer
- Priority: ES200700378 20070206
- International Application: PCT/ES2008/070015 WO 20080204
- International Announcement: WO2008/096028 WO 20080814
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H15/00 ; C12P19/56
Abstract:
The present invention provides compounds characterized by the formula (I), where each of the substituent radicals is described in the specification. The invention also describes the use of said compounds in the treatment of various diseases, including: cancer or tumoral processes in general, Paget's disease, hypercalcaemia, hypercalciuria and neurological diseases (inter alia, Parkinson's, Alzheimer's, Huntington's).
Public/Granted literature
- US20100086973A1 GLYCOSYLATE DERIVATIVES OF MITHRAMYCIN, METHOD OF PREPARATION AND USES THEREOF Public/Granted day:2010-04-08
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