Invention Grant
US08426397B2 3 (3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine derivatives
有权
3（3-嘧啶-2-基苄基）-1,2,4-三唑并[4,3-b]哒嗪衍生物
![3 (3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine derivatives](/docs/US/2013-04-23/US08426397B2/abs.jpg.600x600.jpg)
- Patent Title: 3 (3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine derivatives
- Patent Title (中): 3（3-嘧啶-2-基苄基）-1,2,4-三唑并[4,3-b]哒嗪衍生物
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Application No.: US13141447Application Date: 2009-11-26
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Publication No.: US08426397B2Publication Date: 2013-04-23
- Inventor: Dieter Dorsch , Oliver Schadt , Frank Stieber , Andree Blaukat
- Applicant: Dieter Dorsch , Oliver Schadt , Frank Stieber , Andree Blaukat
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
- Current Assignee: Merck Patent Gesellschaft mit Beschränkter Haftung
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE102008062825 20081223
- International Application: PCT/EP2009/008442 WO 20091126
- International Announcement: WO2010/072301 WO 20100701
- Main IPC: A61K31/33
- IPC: A61K31/33
![3 (3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine derivatives](/abs-image/US/2013/04/23/US08426397B2/abs.jpg.150x150.jpg)
Abstract:
Compounds of the formula (I), in which R1, R2, R3, R3′, R4 have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.
Public/Granted literature
- US20110257173A1 3 (3-Pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine derivatives Public/Granted day:2011-10-20
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