Invention Grant
- Patent Title: Protease inhibitors
- Patent Title (中): 蛋白酶抑制剂
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Application No.: US13541519Application Date: 2012-07-03
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Publication No.: US08426421B2Publication Date: 2013-04-23
- Inventor: Lourdes Salvador Odén , Magnus Nilsson , Pia Kahnberg , Bertil Samuelsson , Urszula Grabowska
- Applicant: Lourdes Salvador Odén , Magnus Nilsson , Pia Kahnberg , Bertil Samuelsson , Urszula Grabowska
- Applicant Address: SE Huddinge
- Assignee: Medivir AB
- Current Assignee: Medivir AB
- Current Assignee Address: SE Huddinge
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: GB0817424.5 20080924
- Main IPC: A61K31/496
- IPC: A61K31/496
Abstract:
Compounds of the formula II: wherein R1 and R2 are independently H, F or CH3; or R1 forms an ethynyl bond and R2 is H or optionally substituted C3-C6 cycloalkyl; R3 is (optionally substituted) C1-C3 alkyl or C3-C6 cycloalkyl; R4 is methyl or fluoro; m is 0-2; E is optionally substituted thiazolyl; A1 and A2 together define an optionally substituted piperazine or piperidine ring have utility in the treatment of osteoporosis, osteoarthritis, rheumatoid arthritis or bone metastases.
Public/Granted literature
- US20120289519A1 PROTEASE INHIBITORS Public/Granted day:2012-11-15
Information query
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