Invention Grant
- Patent Title: EGFR kinase knockdown via electrophilically enhanced inhibitors
- Patent Title (中): EGFR激酶通过亲电增强抑制剂敲低
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Application No.: US12329445Application Date: 2008-12-05
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Publication No.: US08426428B2Publication Date: 2013-04-23
- Inventor: Richard Miller
- Applicant: Richard Miller
- Applicant Address: US CA South San Francisco
- Assignee: Principia Biopharma, Inc.
- Current Assignee: Principia Biopharma, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P35/00 ; A61P29/00
Abstract:
Provided herein are electrophilically enhanced kinase inhibitors of Formula I. Also provided herein are methods of making and utilizing the same.
Public/Granted literature
- US20100144705A1 EGFR KINASE KNOCKDOWN VIA ELECTROPHILICALLY ENHANCED INHIBITORS Public/Granted day:2010-06-10
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